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Whats the relationship between hypokalemia and fluid retention,?

how does hypokalemia cause fluid retention……..??????????

Chosen Answer:

Well, it’s a little more complicated than it looks.

Fluid retention can occur for a broad number of reasons–renal insufficiency is one, as is congestive heart failure, but there’s a numbe of endocrine/metabolic things, like SIADH, that can drive it.

Serum potassium can be driven down by:

*Diuretics, most of which cause loss of potassium (Check Lasix and HCTZ, but exceptions would be spironolactone and triamterine and amiloride, which can cause potassium to rise)

*Dilution, which involves either failure to excrete water adequately, or ingestion of massive amounts of water–I’ve handled both, actually

*Shifts of potassium from the bloodstream into the cells; one of the commonest (although by no means the only) things that will drive that is a good sized dose of insulin dropping a high blood sugar rapidly enough; I’ve had to handle that mess, too

There are others, but that’s a good start.
by: gandalf
on: 8th April 06